Building better systems for the critical industries we can no longer afford to get wrong.

Patrice Bonfiglio is a CEO and institutional investor who believes the greatest challenges facing our most important industries aren’t people problems—they’re systems problems. Through research, investment, and company building, she develops integrated models that help organizations prevent burnout, build resilience, and perform better.
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Patrice Bonfiglio.

Redefining resilience for a new era.

Patrice refuses to normalize burnout. For more than two decades, she has worked at the intersection of healthcare, capital, and organizational leadership, challenging the belief that burnout is an inevitable consequence of modern work. Instead, her work has always been driven by a broader conviction: the greatest barriers to human health, resilience, and performance aren’t individual—they’re systemic.

Through Iris International and her work as an investor and operator, she develops integrated models that replace fragmentation with coordination—helping organizations build resilience by design, not by demanding more from people.

CEO,
Iris International

A venture studio unifying fragmented industries into high performing ecosystems - beginning with healthcare.

Author,
The Burnout Imperative

A powerful wake-up call for high-achievers, business leaders, and organizations ready to confront the hidden costs of burnout, and a blueprint to fix it.

Podcast Host
The Burnout Club

Challenging the conventional understanding of burnout, one expert and one story at a time.

Help shape the future of critical industries.